Final Advice for Space Cadets It goes from one joint to another TIBIA [I thought bar hoppers]
"Filthy" dough LUCRE ["filthy lucre" is/was a common expression]
Creeping joints KNEES
Piano players HANDS
Ready followers? SETGO [I thought willing advocates]
Pin cushion? MAT [in wrestling]
Dispossesor? EXORCIST
Doughnut for the road SPARE
Big name in compacts ESTEE [I thought cars]
GRASPINGATSTRAWS, suggesting desperation, doesn't seem to fit the other theme answers which suggest "being out of it."
NOTES:
/ SLASH [it's a virgule, but
slash has become more popular]
Theme:
In Music Theory... INLALALAND [
la refers to a musical sound]